Invent with us.

13 Jan, 2021
Your Role:  Reporting directly into the Head of Novel Modalities R&D, the Principal Process Scientist will work in the newly created Novel Modalities R&D organization to develop innovative manufacturing technologies for RNA lipid nanoparticles / liposomes.  You will drive innovation for R&D activities securing IP for internal MilliporeSigma technology and product platforms whenever suitable.  You will be responsible for identifying optimized solutions while considering newest scientific data sources and interactions with the scientific community.  You will also be responsible for staying updated on product and industry knowledge as well as “best-in-class” manufacturing technologies.  Additional responsibilities include:  Leading the development efforts to deliver project milestones on-time and on-quality Drive implementation of digital tools and solutions in the development and manufacturing...
Merck St. Louis, MO, USA Process Engineer
13 Jan, 2021
WHO WE ARE: We are a leading science and technology company. Our life science business offers a broad range of innovative products and services to biotech and pharmaceutical drug therapies businesses. Through dedicated collaboration with the scientific and engineering communities, and as one of the top three R&D investors in the life science tools industry, the brand serves as a strategic partner to customers and helps advance the promise of life science.    YOUR ROLE: As Process Scientist – Viral Clearance you will design and deliver Viral Clearance validation studies for biopharmaceutical companies across the APAC region. Within the Process Solutions Services team, you will have scientific expertise in Viral Clearance with in-depth understanding of biopharma downstream processing (chromatography, virus filtration and low pH/chemical inactivation) and virology. You will ensure projects are carried out with the appropriate...
Merck Singapore Process Engineer
13 Jan, 2021
Your Role:   The ideal candidate will lead a team of 4 people to accomplish bio-conjugation process chemistry technology transfer and development campaigns designed to deliver robust and cost-effective production processes to GMP manufacturing. Leverage experience in protein biochemistry and/or conjugation chemistry to on-board/develop, optimize, and scale-up bio-conjugation process chemistry unit operations Effectively work with key stakeholders to technology transfer time-sensitive bio-conjugation production processes to GMP manufacturing Troubleshoot bio-conjugate production process non-conformances and deliver data-driven solutions Responsible for day-to-day management of direct reports and projects Exempt role and extended days and/or possible weekend shifts for special projects occur occasionally throughout the year   Physical Attributes: Perform moderately physical activity. While performing the duties of...
Merck St. Louis, MO, USA Process Engineer
13 Jan, 2021
Your role MilliporeSigma is looking for a Process Development Scientist to join the technical branch of the commercial organization in Raleigh-Durham, North Carolina.  The Process Development Scientist is part of a worldwide team of engineers and scientists reporting into the technical support group for MilliporeSigma’s Process Solutions business.  The ideal candidate will be a scientist/engineer with an in-depth knowledge and understanding of bioprocess unit operations. Travel required up to 25% within North America region with some international travel. Proactively pursuing and performing process development studies for the purification of therapeutic proteins and other modalities using MilliporeSigma technologies such as sterile filtration, depth filtration, tangential flow filtration, viral reduction filtration, as well as, chromatography. Involvement in selection and sizing, process optimization, and technology transfer activities...
Merck Charlotte, NC, USA Process Engineer
13 Jan, 2021
Your Role: At MilliporeSigma in Sheboygan Falls, WI we are seeking a Scientist to develop and evaluate new potential competitive products, technologies, and experimental plans in support of marketing campaigns and initiatives. Responsibilities: Develop, improve, or optimize processes to support ongoing research and custom chemical manufacturing Design and execute experiments with the goal to improve/optimize reaction conditions, raw materials costs and isolated yields Transfer the developed process technology to qualification and/or production via departmentally supported procedures Maintain databases, document work and results accurately and generate technical reports Contribute as individual contributor and work as a team to achieve goals, including meeting deadlines and productivity markers Execute appropriate on-line and literature searches in support of assigned work and/or troubleshooting Interpret spectral and other analytical data...
Merck Sheboygan Falls, WI, USA Process Engineer
13 Jan, 2021
Your Role   At MilliporeSigma, an exciting opportunity now exists to be a member of a critical Life Science manufacturing facility. In this role, you will assist and lead the research and troubleshooting of defective products in order to identify potential root cause failure. You will identify key process parameters, define their impact on product quality, and subsequently develop and modify formulations, methods and controls to meet quality specifications. Your processing insights will be used to recommend and implement improvements, modifications, or additions to document work. Additionally, you will support the maintenance of production records and documents.   The facility is highly team-oriented, so the opportunity exists to attend and/or lead cross-functional meetings with R&D, Engineering, and Operations teams. You will work with outside contractors and other vendors to manage changes to site automation...
Merck Kankakee, IL, USA Process Engineer
13 Jan, 2021
Your role: MilliporeSigma is seeking a highly motivated and creative individual to be a part of a cutting-edge gene therapy process development team. As part of a dynamic organization and global leader in life sciences, the successful candidate will work as a Process Development team member to develop upstream and downstream viral vector processes, execute process characterization studies, support process validation, and execute analytical testing. You will also provide input for areas of innovation, new product development, and technical representation to advance the field of viral therapy.   Primary lead and scientific resource for a wide variety of internal and client-driven projects to develop cGMP compatible viral vector production processes.  Responsible for understanding the scope of work, generating all related documentation, executing the studies, developing and executing analytical assays, analyzing results, and writing development...
Merck Carlsbad, CA, USA Process Engineer
13 Jan, 2021
Your Role: We have a new opening for Process Engineer at the Pyeongtaek Facility. Primary responsibilities include process engineering support of the operations team in the blending of CMP formulations.   Specific responsibilities include: Support process development from initial engineering feasibility through manufacturing implementation including verification and validation activities, equipment qualification, and initial production Drive Operations improvement programs, implement SPC/SQC and other statistical techniques to monitor and reduce variation in manufacturing processes, and develop and conduct training to support this effort. Support SPC/SQC data requirements for both commercialized and pre-commercialized materials. Develop data bases for customized control charts that include raw material, supplier data, in process, finished goods and CofA parameters. Participate in regular manufacturing planning sessions, PCS trend...
Merck Pyeongtaek-si, Gyeonggi-do, South Korea Process Engineer
13 Jan, 2021
Your role:   In this role, you will work with other technology team members including materials scientists, device, process and electrical test engineers to solve time critical technology challenges and develop unique solutions for customers in collaborative development partnerships.   You will have the opportunity to Drive improvements in ALD systems and process workflows (substrate treatments, post deposition anneals etc.) to enable reliable and efficient deposition of various materials with different target unit film material properties (crystallographic phase, resistivity, dielectric function etc.). Work independently to develop ALD or ALE processes of various materials for use as functional/active layers in memory device stacks while interfacing with other team members/groups to utilize these layers in devices that meet or exceed customer specifications (e.g. J, EOT etc.). Connect process conditions, physical characterization, and...
Merck San Jose, CA, USA Process Engineer
13 Jan, 2021
The Role: Coordinate the plant cross-functional team (Engineering, EHS and Quality Departments) during NPI projects and provide technical advice on process engineering requirements as needed. Liaise with, and leverage counterparts, in other sites; Act as key interface between the process development chemists & operations to ensure efficient transfer of processes from laboratory to plant manufacturing. Coordinate the production aspects associated with introduction of new equipment/technology. Develop an understanding of the equipment & technical ability of the processing areas of the site so as to be able to both suggest improvements, and assess how to best accommodate new projects into the existing operation & available technologies Identify “best practice” processes to maintain industry leadership, driving continuous improvements through the use of Lean, Six Sigma methodologies. Propose and implement sustainable...
Merck Arklow, County Wicklow, Ireland Process Engineer
13 Jan, 2021
Job Purpose A senior technical role, responsible to provide system related scientific solutions to customer problems, furthering our competitive positioning.   Key Accountabilities Implementation product support for tangential flow filtration, chromatography, mixers, automation platform, analytical software, etc. at customer site. Facility start-up activities i.e., training, first run support, technical troubleshooting, etc. Confirm soundness of sizing, process parameters, engineering estimates, design review, technical review. Carry out reviews/audits to examine process sequence, operation protocol, design parameters; Troubleshoot field application related issues In-house hydromechanics engineering study and modelling with scientific approach. Technical consultation, both remote and on-site for facility, equipment and process. Coordinate project related activities and communicate project status and updates to all relevant...
Merck Shanghai, China Process Engineer
13 Jan, 2021
Your role   The Process Engineer will work in a dynamic environment supporting the manufacture and testing of high purity filters with a focus on safety, quality, process control/improvements, electro-mechanical assembly and material handling.  The successful candidate will be an enthusiastic team player with high energy and strong engineering skills.  Maintains efficiency and upkeep of critical manufacturing equipment through effective troubleshooting techniques. Identifies and improves yield loss and scrap opportunities. Develops and recommends new testing processes and technologies to achieve cost-effectiveness and improved product quality. Establishes operating equipment specifications and improves manufacturing techniques. Inspects performance of machinery, equipment, and tools to verify their efficiency and investigates and initiates corrective action of problems and deficiencies to ensure product quality. Develops manufacturing...
Merck Jaffrey, NH, USA Process Engineer
13 Jan, 2021
Your role: The Process Engineer will work in a dynamic environment supporting the manufacture and testing of high purity filters with a focus on quality, process control/improvements, electro-mechanical assembly and material handling.  The successful candidate will be an enthusiastic team player with high energy and strong engineering skills.  Maintains efficiency and upkeep of critical manufacturing equipment through effective troubleshooting techniques. Identifies and improves yield loss and scrap opportunities. Develops and recommends new testing processes and technologies to achieve cost effectiveness and improved product quality. Establishes operating equipment specifications and improves manufacturing techniques. Inspects performance of machinery, equipment and tools to verify their efficiency and investigates and initiates corrective action of problems and deficiencies to ensure product quality. Develops manufacturing processes...
Merck Jaffrey, NH, USA Process Engineer
15 Dec, 2020
Job Description   Our Engineers support internal and external manufacturing operations remain operational, continuously improve and innovate. With our extensive range of facilities and environments, our Engineers have opportunities across many diverse areas including Biological, Chemical, Automation, Capital Projects, Maintenance, Safety, Process Development, Technical Services, Utilities and Validation   Reporting into a Director Pharmaceutical Technical Operations – External Manufacturing , the Associate Director Engineering will be responsible for leading the technical interface with strategic external partners at the Focus Factory level. This leader will be a member of External Manufacturing Technology group within Pharm Technical Operations - External organization. This role acts as the technical interface between the company and Contract Manufacturing Organizations (CMO)   Position Description: The incumbent will provide technical...
Merck Lansdale, Pennsylvania, USA Chartered Engineer
15 Dec, 2020
Job Description   Our Engineers support internal and external manufacturing operations remain operational, continuously improve and innovate. With our extensive range of facilities and environments, our Engineers have opportunities across many diverse areas including Chemical, Automation, Capital Projects, Maintenance, Safety, Process Development, Technical Services, Utilities and Validation.   The Senior Specialist Engineer will independently or as a team leader, plan, design, and implement varied technical projects and investigations requiring knowledge of engineering and/or the physical sciences.   The role requires expertise and full application of sound scientific principles, theories, concepts, techniques, and project management skills, as well as a working knowledge of our Company's methods, standards, procedures, and practice   The incumbent is expected to collect and interpret information and develop solutions to projects of...
Merck Riverside, Pennsylvania, USA Chartered Engineer Process Engineer
15 Dec, 2020
Job Description   As a senior scientist in our company's Biologics Process Research & Development (BPRD), you will work with a highly collaborative team of scientists and engineers to design and develop upstream microbial and cell culture process to innovate and support our Company's biologic pipelines and production platforms. This position will have the opportunity to apply and integrate innovation into biologic process sciences to establish our Company as the industry leader in next-generation biologics manufacturing. In addition, we work closely with colleagues in Discovery, Pre-clinical, and Early Development to rapidly develop manufacturing processes for diverse biotherapeutics, and efficiently manufacture material to supply clinical trials. We are also responsible for late stage/commercial process development and the development of new manufacturing technologies. We work with our partners in our company's Manufacturing Division to commercialize and launch...
Merck Kenilworth, NJ, USA Process Engineer
15 Dec, 2020
Job Description   Our company is currently seeking a qualified synthetic organic chemist to join the Discovery Process Chemistry group at our South San Francisco, California site.   The core responsibility of the successful candidate will be to lead a team of scientists in the development of innovative solutions to complex chemistry problems across a diverse portfolio of projects in the discovery phase from lead identification through candidate selection.  The scientist is responsible for defining scalable synthetic routes and optimizing reactions and processes with the goal of expanding Structure-Activity Relationship exploration and accelerating the transition of candidate compounds to early development, as well as managing supply of Active Pharmaceutical Ingredients at varying scales during this period.  Close collaboration with colleagues in Process Chemistry, Medicinal Chemistry, and enabling technologies, as well as a broad array of other...
Merck Remote (South San Francisco, CA, USA) Process Engineer
15 Dec, 2020
Job Description   Are you looking for an exciting opportunity with a rapidly growing pharmaceutical manufacturer? If so, then this is the opportunity for you!   Our Engineers support internal and external manufacturing operations remain operational, continuously improve and innovate. With our extensive range of facilities and environments, our Engineers have opportunities across many diverse areas including Biological, Chemical, Automation, Capital Projects, Maintenance, Safety, Process Development, Technical Services, Utilities and Validation.     At our Company's facility in Elkton, Virginia, the Antibiotic Filling Technical Operations team is seeking highly motivated individuals to provide technical and engineering support to processes and projects in the area as a Technical Operations Process Engineer.  The manufacturing facility is located in the Shenandoah Valley along the Shenandoah River and the Blue Ridge Mountains, a short...
Merck Elkton, VA, USA Process Engineer
15 Dec, 2020
Job Description   Our Engineers support internal and external manufacturing operations remain operational, continuously improve and innovate. With our extensive range of facilities and environments, our Engineers have opportunities across many diverse areas including Biological, Chemical, Automation, Capital Projects, Maintenance, Safety, Process Development, Technical Services, Utilities and Validation.    The successful candidate will have the opportunity to apply his or her enthusiasm and technical skills as a member of a multidisciplinary team supporting the operation and improvement of a manufacturing facility. This role requires the ability to manage multiple projects and activities. Strong communication and collaboration skills are essential, and will require robust problem solving skills and an applied approach to troubleshooting and investigation.   This role will work under the guidance of the Technical Lead for Antibiotic and...
Merck Elkton, VA, USA Process Engineer