13 Jan, 2021

Principal Process Scientis

  • Merck
  • St. Louis, MO, USA
Process Engineer   Biochemicals / Pharmaceuticals

Job Description

Your Role: Reporting directly into the Head of Novel Modalities R&D, the Principal Process Scientist will work in the newly created Novel Modalities R&D organization to develop innovative manufacturing technologies for RNA lipid nanoparticles / liposomes.  You will drive innovation for R&D activities securing IP for internal MilliporeSigma technology and product platforms whenever suitable.  You will be responsible for identifying optimized solutions while considering newest scientific data sources and interactions with the scientific community.  You will also be responsible for staying updated on product and industry knowledge as well as “best-in-class” manufacturing technologies.  Additional responsibilities include: 

  • Leading the development efforts to deliver project milestones on-time and on-quality
  • Drive implementation of digital tools and solutions in the development and manufacturing disciplines.
  • Establish a team-based approach with other internal organizations, such as marketing, sales, PAD, QC and Manufacturing.
  • Establish relationships in the industry that provide access to direct customer feedback and create opportunities for world-class responsiveness and innovative growth.
  • Deliver timely and comprehensive written and oral communications to both internal and external stakeholders
  • Demonstrate attention to detail in the planning, execution and documentation of experimental work

 

 

Who You Are: 
Minimum Qualification:

  • BS with 8+ years’ experience, MS with 3+ years, or PhD
  • Degree in chemistry, chemical engineering, biochemistry, biology or other related scientific discipline
  • Experienced in preparing nanoparticles / liposomes in an R&D environment
  • Hands on experience with encapsulating small molecules or biological molecules in particles

 

Preferred Qualifications:

  • Ph.D. with 5+ years or MS with 8+ years of working experience in the cGMP/GLP environment in a CMO or CRO and knowledgeable about ICH and FDA guidelines
  • Ph.D. with 5+ years of liposomes preparation, experience with Ethanol injection method such as microfluidics system is a strong plus
  • Experience with large scale liposomes preparation and TFF operation
  • Experience with RNA therapeutic drugs
  • Ability to train and coach employees.
  • Experience with technology transfer and scale-up to manufacturing process
  • Experience in process analytical technologies and automation
 
Job Requisition ID:  213906
Location:  St. Louis
Career Level:  D - Professional (4-9 years)
Working time model:  full-time

Careers during Covid-19
Thank you for visiting our careers website, we are always looking for curious minds to join our teams. We understand how much the world is being impacted by the Covid-19 crisis and we want to assure you that your safety is very important to us. To ensure that everyone’s health is protected, instead of a standard face-to-face interview, it is likely that you will be offered alternative digital interview options.

US Disclosure
The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law.  This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.

North America Disclosure
The Company is committed to accessibility in its workplaces, including during the job application process. Applicants who may require accommodation during the application process should speak with our HR Services team at 855 444 5678 from 8:00am to 5:30pm ET Monday through Friday.


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